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Human brain and what are their consequences for the sources and frequen. €¢ What are the evolutionary forces driving the rapid evolution of the Which appears to be the result of both genetic and environmental variables,Īnd developing effective strategies for their treatment and/or prevention isĪ major contemporary challenge for medicine and biomedical research. Understanding the etiology of these multi-factorial diseases, each of Obsessive-compulsive disorder, conditions that in aggregate affect 2-3% ofĪdults. The central nervous system (CNS) such as schizophrenia, bipolar disease and Responsible for the enhanced functional abilities of the human brain but areĪlso error prone and likely to contribute to common complex disorders of These complex developmental programs and processes not only are That are higher in primates than in other organisms Genes implicated in the development of the human central nervous system

Sociated with accelerated rates of evolution of the protein products of the Molecular analysis suggests that these human-specific characteristics are as. Times larger than that of our nearest primate ancestors. In the human cerebral cortex, a multilayered structure that is roughly 3

Of a complex, prolonged developmental history that involves expression ofĪbout half of the genes in our genome and proliferation, migration, andĭifferentiation of scores of different cell types. These functional abilities are the result Sophisticated thoughts, memories, perceptions, and language that distin. The human brain, especially our cerebral cortex, is responsible for the To knowing how the brain contributes to normalįunction and susceptibility to neuropsychiatric disease? Understanding the complex, linked interactionsĪmong the many types of neurons in the brain lead Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages. Below is the uncorrected machine-read text of this chapter, intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text of each book.